Read full story

Methandienone oral is an inbred anabolic steroid originally synthesized by Dr. John Ziegler and released in the US in the early 1960s by Ciba. Initially, methandrostenolone was used to accelerate the recovery and treatment of burns and even to increase the overall tone in women, and soon became widespread in bodybuilding as a means to increase muscle mass, until it was banned by the FDA. Nevertheless, Danabol is still available without prescriptions in countries such as Mexico, in many Asian countries and in Eastern Europe.what is methandienone

Known also under the names: Dianabol, Danabol, Nerobol, Naposim, DBOL, Methandienone in bodybuilding is widely spread slang name “Methane”. Less common brands: Methanoger, Anabolin, Bionabol, Dehydromethyltestosterone, Metasthenol, Novabol, Perabol, Perbolin, Pronabol, Stenolone, Anaboral, Vanabol “Dianoget” and many others) There appeared an injection form of methane Dianoget from Golden Dragon Pharmaceuticals (Hong Kong). To date, there is a large amount of defamatory information about Danabol. The authors exaggerate the toxic properties and underestimate the anabolic activity. Nevertheless, practice shows that a course of methandrostenolone lasting about 6 weeks at a dose of 30 mg per day can increase muscle mass by 8-10 kg, followed by a loss of 2-5 kg. The phenomenon of pullback can be minimized if the course is correctly drawn.

Steroid profile of Methandienone oral

  • Anabolic activity – 200% of testosterone
  • Androgenic activity – 50% of testosterone
  • Aromatization (conversion into estrogens) – yes (low)
  • Toxicity to the liver – moderate
  • Method of reception – orally, injections
  • Duration of action – 6-8 hours
  • Detection time – up to 3 months

Pharmacological action of methandrostenolone

  • The main effect of methandrostenolone is manifested in a rapid increase in muscle mass, due to the activation of protein synthesis, glycogenesis.
  • In passing, the strength indicators
  • Increases appetite
  • Slightly burned fat
  • The bone system is strengthened
  • Methandrostenolone has a relatively weak androgenic effect (50% compared to testosterone), but it does occur in vivo.
  • The studies have shown that side effects begin to appear in most cases when the dose of Danabol exceeds 30 mg per day

Study of the effects of long-term use of Methandienone oral

Data of 6 bodybuilding athletes were studied. Everybody took mantandrostenolone (dianabol) on their own. One of the athletes used the drug continuously for several years, the other 5 took it for 7-10 months with courses ranging from 3 weeks to 3 months with equal breaks to avoid side effects. In addition, a large amount of protein was used, training up to 6 times a week for 2-3 hours.

Blood counts, liver function and endocrine system were assessed, including testosterone, LH, FSH and other laboratory parameters.

Results of clinical analyzes of each athlete who took methandienone:

  • None of the athletes noted violations of sexual function.
  • The blood counts were normal, with one athlete having hemoglobin and hematocrit elevated.
  • On the part of the liver there was a fascination for AST and alkaline phosphatase in 2 subjects.
  • The testosterone level was below the norm in 4 out of 6 subjects who were still on the admission course.
  • LH was significantly decreased in 4 and relatively low in 2.
  • FSH slightly decreased in 3, but significantly elevated in 1.
  • The thyroid hormone thyroxine is normal.
  • At the athlete with the greatest experience of reception of a dianabolum (some years) cholesterol, triglycerides and uric acid have been raised.

Side effects of methandrostenolone


Gynecomastia occurs as a result of the conversion of a portion of methandrostenolone into estrogens, methyl estradiol, which has a 30% greater affinity for estrogen receptors. To prevent the development of this side effect, aromatase inhibitors are used. These drugs in most cases allow to avoid the development of gynecomastia. methandienone dosage

Toxicity to the liver

In view of the fact that methandrostenolone has a methyl group in the 17α position, this drug has a moderate toxic effect on the liver. The methyl group prevents the destruction of Danabol in the liver, and makes it possible to apply the drug orally (orally). This also reduces the binding of Danabol to the sex hormone binding globulin. Choleretic preparations are used, such as Flamin, Tykveol.

Note. Methandienone oral, like any other oral steroid drug, with prolonged reception can provoke thickening of the membranes of the liver cells, as well as worsening of the conductivity of the bile ducts, which can lead to stagnation of bile and pain in the right side. Traditionally, it is advised to drink concomitant drugs such as karsila, essenciale, liv-52, allochol or oozool in order to avoid stagnation of bile and “clean” the liver. These drugs in fact not only do not help the liver during the course, but also harm it. Cholagogue preparations are divided into 2 groups: one strengthens the production of bile – choleretics (allochol, cholenzyme), others – cholekinetics, contribute to its outflow from the gall bladder into the intestine (holosas). Therefore, if you take drugs that promote the formation of bile, you will only aggravate the situation. Therefore, only Holosas can be used on the course of cholagogue! And hepatoprotectors (karsil, essenciale, etc.) have a membrane-stimulating effect on liver cells, which in turn leads to thickening of the hepatic wall and stagnation of bile, which is difficult to diffuse through a thick membrane. So hepatoprotectors are more reasonable to take after the course and in this case it’s better to stop your choice on Heptral and Hepa-merz (ademetionine).

Fluid retention

Another fairly common side effect of methandrostenolone, which is associated with estrogens. At the same time, fluid retention occurs mainly in the muscles, which gives the impression of a larger volume of musculature. After completing the course of methandrostenolone, excess fluid is removed and the weight is reduced by 10-50% of the recruited. This is not observed when using aromatase inhibitors.

Other side effects of Methandienone oral

  • Increase in blood pressure. The problem can be solved if you use aromatase inhibitors during the course.
  • Increased sexual activity during the course and a temporary decline after the course.
  • Atrophy of the testicles occurs with prolonged courses using large doses of Danabol.
  • Acne during the course
  • Heartburn, a feeling of discomfort or a feeling of heat, burning behind the sternum, extending upward from the epigastric (epigastric) area along the esophagus. The appearance of heartburn occurs periodically
  • Alopecia (hair loss)
  • In women, methandrostenolone causes masculinization.
  • In case of abuse or genetic predisposition, the development of myocardial hypertrophy is possible.
  • Hypocoagulant state with a tendency to bleeding, leukemoid syndrome (leukemia, pain in long tubular bones), iron deficiency anemia.
  • Progression of atherosclerosis (increase in LDL concentration and a decrease in HDL cholesterol), peripheral edema.

The course of methandrostenolone

The method of application is described on the basis of literature sources, is presented for informational purposes only and is not a guide to action.

The course of Methandienone oral is carried out by athletes no younger than 21 years to increase muscle mass, in the absence of contraindications (high blood pressure, heart disease, prostatic hypertrophy, liver disease and some others).

  • It is recommended not to exceed the daily dose of more than 30 mg. It is taken in 2-3 doses (eg 20 mg in the morning, 10 after lunch). Methane (Methandienone oral) is toxic to the liver, and the drug is best taken after eating.
  • The course of methandrostenolone begins with 10 mg, after 2-3 days the dose gradually increases to 20-30 mg per day (to assess the tolerance). The duration is usually 6 weeks.
  • In a week it is desirable to connect the aromatase inhibitors. For example, Anastrozole 0.5 mg after 3 days. This will reduce the level of conversion to estrogens, and most importantly eliminate fluid congestion and swelling.
  • 2-3 days after the course, PCT: tamoxifen, 20 mg, 2-4 weeks. During the last week, the dosage is gradually reduced to a complete cancellation.
  • It is necessary to monitor blood pressure. In case of an increase, it is necessary to reduce the dose, or to start taking antihypertensive drugs (Enalapril 5 mg)
  • After the course, you can use a testosterone booster for 3-4 weeks, to more quickly restore the secretion of testosterone in the body and prevent the phenomenon of pullback.
  • Do not forget that the intake of anabolic steroids should be agreed with the doctor, since contraindications are possible.
  • To obtain the maximum effect and reduce the loss of muscle mass after the course, it is recommended to use sports nutrition to gain muscle mass and maintain a diet for muscle mass gain.


Showing all 6 results