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Liothyronine (T3) is a thyroid hormone drug that is often used to burn fat, especially in the context of anabolic steroids. T3 is produced naturally in the body during the development of the thyroid hormone T4 (thyroxine) by the thyroid gland. Oral reception of T3 allows to increase the amount of T3 in the serum to a level that will exceed its amount produced naturally, which accelerates fat burning and in some cases potentially increases the production of GH and activates anabolism.

The instability problem of Liothyronine (T3)

At a dosage of Liothyronine (T3), it is first of all necessary to take into account the fact that the preparation itself is unstable, and this leads to the loss of its activity over time even with the use of pharmaceutical preparations in the form of tablets. Liquid preparations lose their activity even faster. The dosages given below refer to the T3 preparation, which has the maximum activity produced by the pharmaceutical industry in the US or Europe and has not yet lost its shelf life. In many cases, other T3 drugs will contain less, if not much less, T3 than indicated on the label.

For this reason, I recommend looking for a genuine pharmaceutical preparation of T3, preferably of American or European origin. Otherwise, the determination of the necessary dose of the drug may be difficult or deceptive. For example, when using a drug with low activity, a person can decide that “150 mcg” per day is exactly the dose that suits him, but when using a drug with maximum activity, this dose will be too high. liothyronine side effects

Doses of T3

There are two approaches to dosing the Liothyronine (T3), which I recommend.

  1. In the first case, the goal is to achieve a constant level of fat burning or to help keep the body composition close to the personal ideal. The dose of T3 can be very low, preferably 12.5 μg per day, but in some cases up to 25 μg per day. At a low dose, as a rule, the analysis of the thyroid function will not show any inhibition even with prolonged reception. At a high dose, a moderate inhibition of its function is sometimes observed, but the result is much better than in the case when T3 is not accepted, and the depressed function is quickly restored after stopping the use of T3.
  2. In the second approach, the goal is to achieve a significant increase in the rate of fat burning, consciously allowing oppression of the thyroid gland function. The most preferable dose is about 50 μg per day, but in some cases it can be increased to 75 μg per day. Such doses are desirable not always taken, but only for a limited period of time, for example, 8-12 weeks, although there are no exact terms.

The consequences of taking an excessive dose of T3

A high dose of T3, usually starting at about 75 μg per day, but in some cases, with about 100 μg per day, can cause tachycardia (increased heart rate) and muscle weakness and can have a catabolic effect or at least reduce anabolism. Of course, high doses of anabolic steroids often mask the last effect.

Very high levels of T3 are dangerous to the heart.

Side effects

Contrary to popular belief, there is no evidence that prolonged use of high doses of triiodothyronine (as well as thyroxine) inhibits the function of the thyroid gland. In fact, such suppression does not occur, in any case, there is no scientific confirmation of the influence of endogenous triiodothyronine even in very high dosages on the work of “thyroid”, so from this point of view the hormones of the thyroid gland – not only triiodothyronine, but also thyroxine – safe. However, everything is not so good. With long-term use in high doses, triiodothyronine begins to manifestly reveal catabolic abilities (they are present naturally, initially, but the longer the administration, the more catabolic properties of the hormone become stronger), and the destruction in this case is directed not only to the muscles but also to the bone the cloth.

Combination with other drugs

“Classic” is a combination of Liothyronine (T3) with clenbuterol. It is very useful property of triiodothyronine to have a positive effect on the activity of catecholamines (epinephrine, norepinephrine) and thus contribute to the upregulation (increase in the number) of? -adrenoceptors whose agonist is clenbuterol. Good results are obtained using T3 together with testosterone propionate (T3 – 50 μg per day, testosterone propionate 250-350 mg per week) – this combination will avoid loss of muscle mass. The joint use of triiodothyronine, clenbuterol, testosterone propionate and oxandrolone is also shock-fast burning of subcutaneous fat and no loss of muscle mass.

If the task is to lose weight quickly, and you are ready to sacrifice a certain amount of muscle mass, the dosage of triiodothyronine should be significantly increased. The extreme scheme involves the use of T3 at a rate of 2 mcg per kilogram of body weight. That is, a 100-kilogram athlete will need 200 micrograms of triiodothyronine per day. This is not so little, given that clenbuterol will also be present in combination at a fairly high dosage of about 200-240 mg. This combination should be used no more than 3 weeks in a row – first, during this time under the influence of high doses of “maple” there will be a significant down-regulation of? -2-adrenergic receptors and triiodothyronine here will not be able to help, and secondly, three weeks – during which T3 does not yet fully manifest its catabolic “abilities”. In order to even more reduce the influence of the latter, the combination should be used with the support of androgenic preparations, for example, already mentioned testosterone propionate and oxandrolone. Very good results were obtained using T3 in conjunction with IGF-1. True, the increase in muscle mass in this case is unlikely to go, but that’s to get rid of fat deposits will be quite quickly.

How, while taking T3, to prevent the “burning” of muscles?

Many people considered Clenbuterol, Albuterol and other similar drugs because of their alleged anti-catabolic properties to create a balance. Forget about it all. They will not be enough, do not waste time. Liothyronine (T3), by action, will surpass any drug, except for steroids. Therefore, trying to take only T3, only harm the lability of muscle tissue. liothyronine sodium

Anabolic steroids will help to prevent the “expenditure” of muscles. The problem is the right dose. Not all organisms respond equally to drugs, so dosage is a highly personal matter. However, I learned that 250 to 350 mg of testosterone or its equivalent will be enough to conserve precious muscle mass. Because testosterone affects not only the fat mass, but also the muscle mass, you will eventually burn fat faster than usual, without using T3. Summing up, I can say that T3 should not be taken without a muscular-saving dose of steroids.

Testosterone and other steroids, if properly dosed, will stimulate the muscles, and accelerate recovery much faster than normal. You can expect that steroids will be much more effective in building muscle mass, while T3 is its loss. Of course, you can use alternative means, in my case, it was minimal. It was a long-term experiment, using the bod pod indicators, to determine the exact ratio of the fat-free component to the fat mass of the body. When I was on the set of muscle mass, then T3 was necessary for me. I know that many people use it to reduce weight loss, but it can be a powerful tool for mass gain, while minimizing the chance of an increase in fat cells.

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