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Clomiphene Citrate citrate is a synthetic non-steroid drug, reminiscent of the structure of estrogen. It is widely used as an ovulatory stimulant. Having a similarity to estrogen, it can bind to estrogen receptors in the hypothalamus. This prevents the hypothalamus from determining “real” estrogen, and the hypothalamus, in turn, causes the pituitary gland to secrete more gonadotropins, such as FSH and LH. FSH and LH stimulate the ovaries, the testes produce more estrogen in women or testosterone in men.
This property of clomiphene is widely used in the treatment of women with premature ovarian failure and for the induction of ovulation. However, long-term use of this drug is unsafe, since it increases the risk of developing ovarian cancer.
Clomid is recommended for the treatment of women with ovarian dysfunction. Many women who can not get pregnant, ovulation is disturbed. Among patients with ovulation problems, patients with polycystic ovary syndrome and patients with unknown causes of amenorrhea are distinguished. Clomid is prescribed only after a full study of the menstrual cycle and determine the cause of the disorder.
When treating clomid, the time of reception plays a big role. To determine ovulation, the blood is examined and the body temperature is checked. If the fact of ovulation is established, the clomid begins. As a rule, clomid is prescribed on the fifth day of the cycle. Usually clomid is taken within 3-6 cycles. Prolonged treatment with the drug is not recommended.
Clomid is recommended for women with ovarian dysfunction. The following requirements must be met:
- A woman should not be pregnant at this time.
- Absence of ovarian cyst. Before the treatment, every woman must undergo ultrasound to exclude an increase in the ovaries.
- Absence of vaginal bleeding. If there is vaginal bleeding, a woman should be carefully examined to rule out cancer.
- The results of the tests should indicate the normal functioning of the patient’s liver.
Clomid treatment of women with ovulatory dysfunction shows good results. However, its potential for the treatment of male infertility is still not well understood. In Europe and the US, clomid is sometimes used to treat infertility in men. It is proved that clomid causes a surge of LH and FSH, which leads to an increase in the number of spermatozoa. However, there are only data on individual patients, and treatment was conducted only for several months. Judging by the reports of these isolated cases, no side effects were observed in the treatment. But there is an opinion that prolonged therapy with clomiphene can cause men to develop a testicular tumor and gynecomastia.
Why do we need antiestrogens?
Antiestrogens are the best friends of bodybuilders who use androgenic anabolic steroids in their studies. And that’s why.
We all know that on the course of steroids the body ceases to produce its own testosterone hormone. It happens because it simply does not need – from outside it and so much comes, so why waste the resources of the body once again? Thus, the activity of the “pituitary-hypothalamus-testicle” arc, begins to quickly come to naught. And the longer the course lasts, the greater the dosage, the “heavier” the preparations, the stronger this arc “stalls”. By the way, the degree of its “kill” after the course depends on the balance of such hormones as estradiol, prolactin and progesterone. If the level of at least one of these hormones is higher than the reference values, the arc will fall asleep much faster and deeper. That is why it is so important to closely monitor the level of these hormones on the course, take tests, and have prolactin and estradiol inhibitors on hand.
Accordingly, the deeper the pituitary-hypothalamus testicle is immersed, the longer it will have to awaken and the more effort will be required after the course, so that the development of its own testosterone normalizes. And the faster you restore the level of your own testosterone, the better you will look after the course, the faster the loss of muscle mass and strength will stop.
Why do we need antiestrogens? Here, then, anti-estrogens come to our aid. These are: clomiphene citrate (clomid), tamoxifen citrate and torimifene citrate. We will not talk about the last two, the second one in general should be excluded from this list, since it is the most “dirty”, and often from the restoration of tamoxifen you can get more minuses than pluses.
For all athletes involved in bodybuilding, the use of clomid is recommended. Concerning other antiestrogens, it is expensive, but precisely the most qualitative and effective. And it’s the last thing to save on health.
Principle of work of Clomiphene Citrate
The principle of the work of clomiphene citrate It can often be seen how athletes on post-course therapy use various dietary supplements to restore their own production of testosterone. Tinctures of herbs, tribulus, and other, I apologize for the expression, trash. This is not true. After the AAS course, the body is in a deep hormone well because the level of luteinizing and follicle-stimulating hormones is zero. These are gonadotropic hormones, the amount of which determines the level of testosterone in the blood.
Clomid directly affects the level of LH and FSH. In addition, he joins estrogen receptors, so there will be a lot of estrogen, judging by blood analysis, but most of it will simply be inactive.
In the first days after taking the clomid after the course, the levels of LH and FSH soar to the upper maximum values, very quickly raising the level of testosterone. Thus, in a few weeks (2-6), we get a perfectly normal level of testosterone, while the levels of LH and FSH after the drug is withdrawn will return to their normal normal values. About the number of weeks – all individually. Someone will recover in 2 weeks, someone needs 2 months. Depends, again, on what the course was.
Dosage of Clomid for bodybuilders
Clomid is taken only once a day. Experts in the field of bodybuilding are advised to take it alone or in combination with anabolic steroids of low activity. Most bodybuilders take anabolic steroids for several months and then switch to clomid. The clomid provides a burst of testosterone. The exact time when you should start taking clomid is unknown. But there is a recommendation to start taking clomid 7-10 days after the end of taking steroid drugs.
Very many athletes and bodybuilders take clomid, but use different doses at the same time. Medical recommendations for taking this drug to those who are engaged in bodybuilding, does not exist. But the dosage was established by practical means. Most bodybuilders take clomiphene for two weeks at 50-100 mg per day. Some bodybuilders recommend increasing the dose to 100 mg per day. Do not take clomid for more than three weeks. This cyclicity was established by bodybuilders of the past. Since doctors do not recommend taking clomid to bodybuilders, it is very difficult to get a medical advice on taking this medication. In any case, if there are doubts about taking clomid, you can consult with specialists in the treatment of infertility: they know the effect of this drug best of all.
It is not known exactly how long it takes to take clomid. There is no evidence of long-term treatment with this drug. There is only a general recommendation not to take clomid long courses.
Reviews about Clomiphene Citrate in bodybuilding
Any negative feedback about the use of clomid in bodybuilding is absent. Unsurprisingly, because the side effects of the drug are absent (at least, not observed). Clomiphene citrate helps athletes recover quickly and suffer minimal losses after a course of steroids.
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